Pronefra® Liquid Kidney Support for Cats & Dogs 60 ml

Pronefra® Liquid Kidney Support for Cats & Dogs 60 ml

Chronic kidney disease (CKD) is the leading cause of death in cats over 7 years old — and one of the most common serious conditions in senior dogs. Pronefra is Bioiberica's veterinary-developed liquid kidney support supplement — a clinically researched oral formula that works alongside standard CKD management to reduce the phosphate and uremic toxin accumulation that accelerates kidney function decline. Designed to be administered directly or mixed with food, Pronefra supports the management of CKD at every stage — helping to maintain quality of life, slow disease progression, and support the overall wellbeing of cats and dogs living with compromised kidney function. At EGP — per 60ml bottle, this is the veterinary-recommended supplement that responsible CKD management includes.

⚠️ Veterinary Supplement — Use under veterinary guidance for pets diagnosed with kidney disease.

Why Pronefra Is the Best Choice for Kidney Support in Cats & Dogs

• Chitosan — Uremic Toxin Binder — Chitosan (a natural polysaccharide derived from crustacean shells) binds uremic toxins in the gastrointestinal tract — reducing their absorption into the bloodstream and decreasing the circulating toxin load that compromised kidneys struggle to filter, directly supporting the symptom management of CKD.
• Calcium Carbonate — Phosphate Binder — Excess phosphate accumulation is one of the primary drivers of CKD progression — calcium carbonate binds dietary phosphate in the gut before it can be absorbed, reducing serum phosphate levels and slowing the renal deterioration that elevated phosphate accelerates.
• Essential Amino Acids & B Vitamins — CKD patients experience protein-calorie malnutrition and B vitamin depletion through increased urinary losses — Pronefra's amino acid and B vitamin content helps address these nutritional deficits that contribute to muscle wasting and reduced quality of life.
• Liquid Format — Maximum Palatability & Dosing Flexibility — The liquid formulation allows precise dosing by body weight, easy mixing into food for reluctant patients, and rapid onset of action compared to tablet formats — critical for CKD patients whose appetite and compliance may already be compromised.
• Clinically Researched Formula — Pronefra's active ingredients are supported by peer-reviewed veterinary research demonstrating efficacy in reducing phosphate and uremic toxin levels in CKD patients — not a general "kidney support" supplement but a formula with documented clinical mechanisms.
• Suitable for Both Cats & Dogs — Dosed appropriately by body weight for both species — one product covers multi-pet households where both a cat and a dog may require kidney support.
• Bioiberica Veterinary Pedigree — Bioiberica is a Spanish veterinary pharmaceutical company with decades of research in animal health — a manufacturer whose formulations meet pharmaceutical-grade quality and efficacy standards.

Product Details & Clinical Information

Understanding CKD — The Progressive Kidney Challenge — Chronic kidney disease is defined by the irreversible loss of functional kidney tissue (nephrons) over time. As nephrons are lost, the remaining tissue works harder to compensate — but this compensatory hyperfiltration accelerates the deterioration of remaining nephrons, creating a progressive downward spiral. Two key biochemical changes drive this progression and its symptoms: phosphate retention (as failing kidneys cannot excrete phosphate efficiently) and uremic toxin accumulation (as failing kidneys cannot filter metabolic waste products). Both accumulations are directly toxic to remaining kidney tissue — accelerating the very decline they result from. Managing these two accumulations is the cornerstone of CKD medical management, and it is precisely what Pronefra's active ingredients address.

Chitosan — How It Works — Chitosan is a positively charged polymer that binds negatively charged uremic toxins (including indoxyl sulfate, p-cresyl sulfate, and urea) in the gastrointestinal tract through ionic interaction. By binding these toxins in the gut before they can be absorbed into the portal circulation, chitosan reduces the systemic uremic toxin burden that contributes to uremic syndrome symptoms — nausea, lethargy, loss of appetite, and the progressive organ damage that high uremic toxin levels cause. This mechanism is analogous to the gastrointestinal phosphate binding provided by calcium carbonate, working synergistically to address both major pathological accumulations of CKD simultaneously.

Calcium Carbonate — Phosphate Management — When calcium carbonate reaches the stomach, it reacts with stomach acid to release calcium ions, which then bind to dietary phosphate in the small intestine before it can be absorbed. The resulting calcium phosphate complex is excreted in feces rather than entering the bloodstream. This is the same phosphate-binding mechanism used in veterinary prescription renal diets, applied here as a supplement that can be used alongside or in addition to dietary phosphate restriction — providing additive phosphate control.

Amino Acids & B Vitamins — Addressing CKD Malnutrition — CKD patients are at high risk of protein-energy malnutrition for two reasons: reduced appetite (driven by uremic toxin accumulation causing nausea) and increased protein and B vitamin losses through damaged glomerular filtration. Muscle wasting and weight loss in CKD cats and dogs are not merely consequences of not eating enough — they reflect genuine metabolic and nutritional depletion that amino acid supplementation can partially address. B vitamins (particularly B1, B6, and B12) are water-soluble and lost in excess through the polyuric state that early CKD produces.

Liquid Format — Clinical Rationale — CKD patients frequently experience reduced appetite and food selectivity — making tablet or capsule administration challenging for extended treatment courses. Pronefra's liquid format can be mixed into small amounts of food, applied to the gum line, or mixed with a small liquid food reward — maximizing compliance across the weeks to months of continuous administration that CKD management requires. Precise dosing by body weight also allows appropriate titration as the patient's condition changes.

The IRIS CKD Staging System — Pronefra is relevant across IRIS CKD Stages 1–4, though its role and dosing strategy may differ by stage. Your veterinarian will advise on appropriate use relative to your pet's IRIS stage, current creatinine and phosphate levels, and concurrent treatment protocol.

Specifications

Key Active Ingredients & Mechanisms:

Pronefra in the CKD Management Protocol:

IRIS CKD Stage Reference:

Dosing Guide (General — Confirm with Veterinarian):

Always confirm dosing with your veterinarian based on your pet's specific condition and IRIS stage.

Administration Methods:

Storage:

⚠️ Important Safety Information

• For veterinary use — Use under the guidance of a licensed veterinarian
• For pets diagnosed with CKD — Not a preventive supplement for healthy kidneys without veterinary indication
• Not for use in pets with hypercalcemia — Calcium carbonate contraindicated in high blood calcium states
• Crustacean-derived chitosan — Not suitable for pets with known shellfish hypersensitivity
• Monitor calcium and phosphate levels — Regular blood panels advised during extended use
• Keep out of reach of children
• Consult your veterinarian for diagnosis, staging, and complete CKD management plan

The Supplement That Gives Kidney Disease Patients More Good Days

A CKD diagnosis is not the end — it is the beginning of a management journey that, done well, can preserve quality of life for months to years beyond what unmanaged disease would allow. Pronefra is one of the tools that makes that management possible: addressing the phosphate and uremic toxin accumulation that drives CKD progression, in a format that even the most reluctant patient can receive daily. For the cat or dog living with kidney disease, Pronefra is the supplement that buys time — more good mornings, more comfortable afternoons, more evenings beside you.

Available at petfast.shop — Egypt's trusted destination for veterinary-grade pet healthcare and supplements, with fast local delivery right to your door.

Always use under veterinary guidance. Consult your veterinarian for diagnosis and treatment planning.

Clinically researched. Precisely formulated. More good days ahead. Add Pronefra® Liquid Kidney Support to your cart today — and give your pet's kidneys the professional support they need.