Virbac SEBOLYTIC SIS for Dog & Cat 250ML VBI

Virbac — SEBOLYTIC SIS | 250ml | Veterinary Keratolytic & Seborrheic Shampoo for Dogs & Cats

The veterinary standard for seborrhea and scaling. Virbac SEBOLYTIC SIS is a veterinary-grade keratolytic and antiseborrheic shampoo formulated with three clinically proven active ingredients — sulfur, iodine, and salicylic acid — specifically designed to treat seborrheic skin conditions, excessive scaling, and keratoseborrheic disorders in dogs and cats. Seborrhea is one of the most common and frustrating dermatological conditions in pets — characterized by abnormal skin cell turnover that produces excessive scaling, greasy or dry skin, unpleasant odor, and secondary bacterial and yeast infections. Standard grooming shampoos cannot address seborrhea — the condition requires the specific keratolytic, keratoplastic, and antimicrobial actions that only veterinary-grade active ingredients can provide. Virbac SEBOLYTIC SIS delivers all three mechanisms simultaneously — salicylic acid dissolves the bonds between abnormal skin cells, sulfur normalizes skin cell turnover and provides antimicrobial action, and iodine provides broad-spectrum antimicrobial coverage against the bacteria and yeast that colonize seborrheic skin. The result: reduced scaling, normalized skin texture, reduced odor, and a healthier skin barrier — from the veterinary dermatology brand that professionals trust. 250ml — the veterinary shampoo that treats seborrhea at its source.

Why Virbac SEBOLYTIC SIS Is The Best Choice

• Triple Active Formula — SIS — Sulfur, Iodine, and Salicylic acid — three clinically proven active ingredients working synergistically to address every aspect of seborrheic skin disease.
• Salicylic Acid — Keratolytic Action — Dissolves the abnormal bonds between hyperkeratotic skin cells — removing scales and allowing normal skin cell turnover to resume.
• Sulfur — Keratoplastic & Antimicrobial — Normalizes the rate of skin cell production (keratoplastic effect) and provides antimicrobial action against the bacteria and yeast that colonize seborrheic skin.
• Iodine — Broad-Spectrum Antimicrobial — Provides broad-spectrum antimicrobial coverage against bacteria, yeast (Malassezia), and fungi — addressing the secondary infections that complicate seborrhea.
• Seborrhea Treatment — Specifically formulated for seborrheic skin conditions — both seborrhea sicca (dry, flaky) and seborrhea oleosa (greasy, oily).
• Keratoseborrheic Disorders — Effective for the full spectrum of keratoseborrheic conditions including primary seborrhea, secondary seborrhea, and scaling disorders.
• Odor Reduction — The antimicrobial action reduces the bacterial and yeast overgrowth that produces the characteristic unpleasant odor of seborrheic skin.
• For Dogs & Cats — Formulated for use in both species — a versatile veterinary shampoo for multi-pet households.
• Virbac — Veterinary Dermatology Expertise — From one of the world's leading animal health companies — the veterinary dermatology brand that professionals trust.
• 250ml — A practical clinical shampoo size for ongoing dermatological management.

(Visual asset placement: flat-lay of the Virbac SEBOLYTIC SIS bottle with the clinical branding prominent, or lifestyle photo of a well-groomed dog or cat with healthy, scale-free skin — communicating the skin health the shampoo restores.)

Product Details & Features

Understanding Seborrhea in Dogs and Cats Seborrhea is a disorder of keratinization — the process by which skin cells are produced, mature, and shed. In normal skin, this process is tightly regulated — skin cells are produced at the base of the epidermis, mature as they migrate to the surface, and are shed invisibly. In seborrhea, this process is dysregulated — skin cells are produced too rapidly, mature abnormally, and accumulate on the skin surface as visible scales.

Types of seborrhea:

Seborrhea sicca (dry seborrhea):

• Characterized by dry, flaky, white or gray scales
• Skin feels dry and rough
• Scales shed easily and accumulate in the coat and environment
• Common in breeds with dry skin tendencies

Seborrhea oleosa (oily seborrhea):

• Characterized by greasy, yellowish scales that adhere to the skin and coat
• Skin feels oily and has a characteristic rancid odor
• Scales are sticky and difficult to remove
• Common in breeds with oily skin tendencies (Cocker Spaniels, Basset Hounds)

Mixed seborrhea:

• Most common presentation — elements of both dry and oily seborrhea
• Variable presentation depending on body region

Primary vs. secondary seborrhea:

Primary seborrhea:

• An inherited disorder of keratinization — the skin cell turnover process is genetically dysregulated
• Breed-specific — most common in Cocker Spaniels, West Highland White Terriers, Basset Hounds, Labrador Retrievers, and Persian cats
• Lifelong condition requiring ongoing management

Secondary seborrhea:

• Seborrhea as a symptom of an underlying condition — the most common presentation
• Underlying causes include: hypothyroidism, hyperadrenocorticism (Cushing's disease), allergies (food or environmental), parasites (Cheyletiella, Demodex), nutritional deficiencies, and other systemic diseases
• Treating the underlying cause resolves the seborrhea — but SEBOLYTIC SIS manages the skin condition while the underlying cause is investigated and treated

The Three Active Ingredients — SIS

Salicylic Acid — The Keratolytic Agent: Salicylic acid is the primary keratolytic ingredient — it works by dissolving the intercellular cement that holds abnormal skin cells together:

Mechanism of action:

• Salicylic acid reduces the pH of the skin surface — creating an acidic environment that dissolves the desmosomes (protein bonds) between corneocytes (surface skin cells)
• This dissolution allows the abnormal, accumulated skin cells to be removed — clearing the scale burden from the skin surface
• The removal of accumulated scales allows the skin to breathe, reduces the substrate for bacterial and yeast growth, and allows topical medications to penetrate more effectively

Clinical effects:

• Visible scale reduction after the first few applications
• Improved skin texture — smoother, less rough
• Reduced scale accumulation in the coat and environment
• Enhanced penetration of other active ingredients (sulfur, iodine) through the cleared skin surface

Sulfur — The Keratoplastic & Antimicrobial Agent: Sulfur provides two distinct and complementary actions:

Keratoplastic action:

• While salicylic acid removes existing abnormal scales (keratolytic), sulfur normalizes the rate of new skin cell production (keratoplastic)
• Sulfur slows the abnormally rapid skin cell turnover that characterizes seborrhea — reducing the rate at which new scales are produced
• The combination of salicylic acid (removing existing scales) and sulfur (slowing new scale production) addresses both the current scale burden and the underlying production abnormality

Antimicrobial action:

• Sulfur has direct antimicrobial activity against bacteria and yeast — particularly Malassezia pachydermatis, the yeast that commonly colonizes seborrheic skin
• Sulfur is metabolized by skin bacteria to hydrogen sulfide and pentathionic acid — compounds with direct antimicrobial activity
• The antimicrobial action reduces the secondary infections that complicate seborrhea and contribute to odor and inflammation

Iodine — The Broad-Spectrum Antimicrobial: Iodine provides the broadest antimicrobial coverage of the three active ingredients:

Mechanism of action:

• Iodine is a potent oxidizing agent that disrupts the cell membranes and metabolic processes of microorganisms
• It is effective against bacteria (gram-positive and gram-negative), yeast (Malassezia), dermatophytes (ringworm fungi), and some viruses

Clinical relevance: Seborrheic skin is particularly susceptible to secondary microbial colonization because:

• The accumulated scales provide a nutrient-rich substrate for bacterial and yeast growth
• The disrupted skin barrier allows microorganisms to penetrate more deeply
• The altered skin pH and lipid composition favor Malassezia overgrowth

Iodine's broad-spectrum antimicrobial action addresses all of these secondary colonizers simultaneously — reducing the microbial burden that contributes to inflammation, odor, and skin damage.

The Synergistic Triple Action The three active ingredients work synergistically — each addressing a different aspect of seborrheic skin disease:

Conditions Treated by SEBOLYTIC SIS

Primary seborrhea: For breeds with inherited keratinization disorders, SEBOLYTIC SIS is used as a long-term management shampoo — regular bathing (typically weekly to bi-weekly) maintains scale control and prevents secondary infections.

Secondary seborrhea: While the underlying cause is investigated and treated, SEBOLYTIC SIS manages the skin condition — reducing scale burden, controlling secondary infections, and improving the pet's comfort and quality of life.

Malassezia dermatitis: Malassezia (yeast) overgrowth is one of the most common complications of seborrhea — and one of the most common causes of skin odor, itching, and inflammation in dogs. The combined antimicrobial action of sulfur and iodine provides effective Malassezia control.

Bacterial pyoderma secondary to seborrhea: The disrupted skin barrier of seborrheic skin is susceptible to bacterial colonization — particularly Staphylococcus pseudintermedius. Iodine's broad-spectrum antibacterial action reduces the bacterial burden on seborrheic skin.

Scaling disorders: Any condition characterized by abnormal scaling — including ichthyosis, zinc-responsive dermatosis, and vitamin A-responsive dermatosis — benefits from the keratolytic action of salicylic acid.

Usage Protocol

Bathing frequency:

• Acute/severe seborrhea: 2–3 times per week initially — reducing to weekly as the condition improves
• Maintenance: Weekly to bi-weekly — maintaining scale control and preventing recurrence
• Primary seborrhea: Ongoing weekly bathing — lifelong management

Application technique:

1. Wet the coat thoroughly with warm water
2. Apply SEBOLYTIC SIS generously — working into a lather
3. Massage thoroughly into the skin — ensuring contact with all affected areas
4. Leave on for 5–10 minutes — contact time is essential for the active ingredients to work
5. Rinse thoroughly with warm water
6. Repeat if necessary for heavily scaled areas

Contact time is critical: Unlike standard grooming shampoos that are applied and immediately rinsed, SEBOLYTIC SIS requires a contact time of 5–10 minutes for the active ingredients to penetrate the scale layer and exert their keratolytic, keratoplastic, and antimicrobial effects. Rinsing immediately after application significantly reduces efficacy.

For cats: Use with caution in cats — ensure thorough rinsing and prevent the cat from licking the shampoo during the contact time. Consult your veterinarian before use in cats with sensitive skin or concurrent skin conditions.

(Visual asset placement: flat-lay of the Virbac SEBOLYTIC SIS bottle with the active ingredients (SIS) prominently displayed, or lifestyle photo of a well-groomed dog with healthy, scale-free, glossy skin — communicating the skin health transformation the shampoo achieves.)

Specifications & Usage

Usage Guidelines

Serving Tips

• Always leave on for 5–10 minutes — Contact time is essential — do not rinse immediately
• Wear gloves — Iodine can stain skin and nails — wear disposable gloves during application
• Protect eyes — Avoid contact with eyes — rinse immediately if contact occurs
• Warm water — Use warm (not hot) water — hot water can irritate seborrheic skin
• Follow with conditioner if needed — Salicylic acid can be drying — a moisturizing conditioner after rinsing can help maintain skin hydration, particularly for seborrhea sicca
• Veterinary diagnosis first — Seborrhea is often secondary to an underlying condition — veterinary diagnosis of the underlying cause is important for complete management

Virbac Dermatology Range at petfast.shop

Keratolytic. Keratoplastic. Antimicrobial. — Backed by petfast.shop

At petfast.shop, Virbac SEBOLYTIC SIS is the veterinary dermatology shampoo we carry for dog and cat owners managing seborrhea, scaling, and keratoseborrheic skin conditions — the triple-action formula of sulfur, iodine, and salicylic acid that removes existing scales, normalizes skin cell turnover, and controls the secondary bacterial and yeast infections that complicate seborrheic skin disease. Veterinary-grade active ingredients. 5–10 minute contact time for maximum efficacy. 250ml of Virbac's dermatology expertise, delivered fast across Egypt from petfast.shop. Because your pet's seborrheic skin deserves the veterinary shampoo that treats the condition — not just the symptoms.

Sulfur. Iodine. Salicylic acid. Triple-action seborrhea treatment. Add Virbac SEBOLYTIC SIS to your cart today — veterinary keratolytic shampoo for dogs and cats, delivered fast across Egypt from petfast.shop.